The layperson likely believes niacin helps with weight loss because they’ve read that it’s involved in metabolism. The drug Niaspan (extended-release niacin) has been on the market since 1997, yet there’s zero evidence to suggest that it causes weight change (gain or loss) at doses of 500 to 2000 mg per day. It is unclear as to why people believe niacin supplements promote weight loss. Niacin & Weight Loss: Why People Think It Works… Nonetheless, a circulating belief among many communities is that niacin supplements can help people lose weight. Although mega-doses of niacin supplements are safe, effective, and tolerable for treating high cholesterol and lipids, they are not regarded as useful for other medical conditions. Fortified foods make it easy for adults living in developed countries to attain the recommended daily allowance (RDA) of niacin set between 16 mg and 18 mg.ĭespite a recommended niacin intake of 16 mg to 18 mg per day for adults, some individuals administer mega-dose niacin supplements (between 500 mg and 2000 mg) for the treatment of hypercholesterolemia and/or hyperlipidemia. In effort to eradicate pellagra (and diseases stemming from vitamin deficiencies), a food fortification program was implemented to enrich food products with vitamins (including niacin). NADP is a coenzyme that modulates anabolic reactions such as synthesis of cholesterol and fatty acids.Īdequate niacin intake is necessary to prevent onset of a medical condition known as pellagra in which symptoms of diarrhea, dermatitis, and dementia occur. NAD is a coenzyme recognized for its involvement in the catabolism of fats, carbohydrates, and proteins, as well as sending signals for DNA repair. Niacin (vitamin B3), also referred to as nicotinic acid, is a human nutrient that functions as a precursor to NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate).
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